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Modifying a well learned/mastered behavior is difficult, but it is more than doable. Describe in detail, automaticity in sport, the challenges in changing a well learned skill and 2 strategies for modifying automatized skills. 

BCH4024 OC Sp25 E2 Q13: Pepsin is produced from pepsinogen within the stomach through a process known as ______.

What is perceptual-cognitive expertise and what are the defining characteristics that separate the expert from the novice and the near-expert? 

Describe the principles of behavior modification and describe the role of augmented feedback and the role of failure in shaping behavior. Please be thoughtful, thorough and use examples in supporting your response. 

BCH4024 OC Sp25 E2 Q22: In cancer chemotherapy, thymidylate synthase is potently inhibited by _________ .

BCH4024 OC Sp25 E2 Q28: Promising drugs have been developed to treat invasive cancers. A class of these drugs act as competitive inhibitors of ATP binding to active sites of receptor tyrosine kinases (RTKs). What are some possible downstream effects of RTK activation in healthy cells?

BCH4024 OC Sp25 E2 Q29: Iodine (I-) is required by the thyroid follicular cells for biosynthesis of thyroid hormones. The Na+I- symporter uses a gradient of Na+ to import I- into these cells. What type of transport is this?

BCH4024 OC Sp25 E2 Q50: What role would an adaptor protein play in a receptor tyrosine kinase signaling pathway? 

BCH4024 OC Sp25 E2 Q41: Common genetic causes of severe adult obesity are loss-of-function mutations in the melanocortin signaling pathway. One effect of these mutations is aberrantly low levels of activated protein kinase A (PKA) in certain cells of the hypothalamus. What type of mutation would most likely produce low levels of activated PKA?

BCH4024 OC Sp25 E2 Q40: If a membrane fatty acid composition resulted in a melting temperature (Tm) or transition temperature of 41°C for the plasma membrane of a hybrid cell, how would the membrane respond to changes in temperature if the cells are induced to express cholesterol?