The following is an excerpt from a recent scientific publica…

The following is an excerpt from a recent scientific publication:“A protein can be identified based on each level of its structure…. The primary structure… linear chain… The quaternary structure… is formed through side‑chain interactions between 2 or more polypeptides.” What distinguishes quaternary from tertiary structure?

The following is an excerpt from a recent scientific publica…

The following is an excerpt from a recent scientific publication:“Covalent molecular docking has been recently implemented in the computer‑aided drug design workflows to describe covalent interactions between inhibitors and biological targets. … these types of inhibitors derive their activity from both non‑covalent interactions and the formation of the covalent bond between the inhibitor and the target protein … covalent docking programs … integrate conventional non‑covalent docking and scoring schemes by modeling the newly formed covalent bond and the interactions occurring at the reaction site.” What key feature distinguishes covalent docking workflows compared to standard noncovalent docking?

The following is an excerpt from a recent scientific publica…

The following is an excerpt from a recent scientific publication:“For most proteins in the genome databases, function is predicted via sequence comparison. In spite of the popularity of this approach, the extent to which it can be reliably applied is unknown. We address this issue by systematically investigating the relationship between protein function and structure. We focus initially on enzymes functionally classified by the Enzyme Commission (EC) and relate these to structurally classified domains the SCOP database. We find that the major SCOP fold classes have different propensities to carry out certain broad categories of functions.” According to the excerpt, which structural classification is most predictive of enzyme functional categories?