Test 1 Review Click on the down arrow to view the test. Plea…

Test 1 Review Click on the down arrow to view the test. Please write your work and answers on your paper and upload your work on the additional content area below. The test is 120 min, but shows 150 minutes so that you have an extra 30 minutes to upload your work. Thank you for taking the re-test. Type “DONE” in the text box, if needed to submit the test.

BONUS: Refer to the following paragraph and accompanying fig…

BONUS: Refer to the following paragraph and accompanying figure to answer the following question(s). Since structure correlates well with function, look for new ways to probe the complex structure of proteins in order to understand what they do and how they do it. One of the most powerful techniques in existence today is X-ray crystallography. The main difficulty with this technique is getting the protein to crystallize. Once crystallized, the protein is bombarded with X-rays to create a pattern that can be analyzed mathematically to determine the protein’s three-dimensional structure. This analysis has been performed by Palczewski (2000) on the protein rhodopsin, which is a light-sensitive protein found in species ranging from ancient bacteria (archaea) to humans. The structure (schematically shown above, where each letter represents an amino acid) is characterized by a single polypeptide chain with several α-helical segments that loop back and forth across the cell membrane. Another notable feature is the disulfide bond (—S—S—) that can be seen at the bottom of the third transmembrane segment. [Figure adapted from K. Palczewski et al., Science 289 (2000): 739.]   Which term best describes the type of membrane protein in the figure? (1 point)  [1] Which of the protein regions (the regions are labeled in the figure with a letter and number)  is likely the ligand binding site for the protein? There are 3 possible answers (4 points)? [2] What is a possible function of this protein (4 points)? [3]