Which of the following is best describing of Bernard Soulier…

Which of the following is best describing of Bernard Soulier Syndrome A. Presence of giant platelets, thrombocytopenia, normal PFA, normal VWF activity, PT and APTT normal, normal platelet aggregation. B. Normal PT and APTT; presence of giant platelets and thrombocytopenia; absent GPIB receptor by flow cytometry C. Normal platelet count; some large platelets; PT and APTT prolonged; prolonged bleeding time and PFA D. Thrombocytosis; abnormal platelet aggregation with ADP, Collagen, and Epinephrine; normal ristocetin.

Chediak Higashi syndrome often develops thrombocytopenia.  T…

Chediak Higashi syndrome often develops thrombocytopenia.  This condition, characterized by a low platelet count, contributes to bleeding tendencies observed in these patients. In addition to thrombocytopenia, Chediak-Higashi patients may also experience anemia and neutropenia. The neutrophils exhibits giant, abnormally large lysosomal granules in the cytoplasm.