Drug A is an anticlotting agent that is chiefly metabolized…

Drug A is an anticlotting agent that is chiefly metabolized by CYP1A2. It was found that patients who smoke >10 cigarettes per day received increased benefit of the drug at a given dose, relative to nonsmokers. This is despite a significantly lower serum concentration of the drug in smokers. Which of the following could best explain these observations?  

Consider the following metabolic pathway and answer the ques…

Consider the following metabolic pathway and answer the question below:                                  Which of the following molecules best fits in box 23? (chemically, not physically)