A 32-year-old previously healthy male software engineer pres…

A 32-year-old previously healthy male software engineer presents urgently to his primary care physician reporting extreme, unquenchable thirst and massive urine output for the past 5 days. He describes drinking 10-15 liters of water per day. Urinating large volumes (estimated 8-12 liters/day) of clear, watery urine, waking him up 5-6 times nightly for restroom. Constant feeling of dry mouth feeling fatigued and slightly lightheaded. No recent illness, head trauma, or surgery. BP 125/80 mmHg (lying), 115/75 mmHg (standing). Pulse 88 bpm Urine appears clear with low specific gravity. Urine osmolarity is 75 mOsm/kg Serum Sodium Na+158 mmol/L, Serum Osmolality: 310 mOsm/kg) ,. Plasma Glucose: normal ADH challenge test shows dramatically decrease in urine output within 1-2 hours. Urine Osmolality rises sharply from 75 mOsm/kg to 650 mOsm/kg. Serum osmolarity and Na+ start to trend down. What is the most appropriate medical treatment of his condition?

A 75-year-old male is found lethargic at home with a blood p…

A 75-year-old male is found lethargic at home with a blood pressure of 100/60 and temperature of 98F.Labs: Na=138 mEq/L, K= 2.8 mEq/L, HCO3=9 mEq/L, Cl=118 mEq/L, Creatinine= 1.0 mg/dL, BUN=20 mg/dL, Ca= 10 mg/dL, PO2=80, PCO2= 25 and pH= 7.29. Urine pH=4.5  What is the most likely cause of the patient’s disorders?  

A 28-year-old man who is receiving lithium treatment for bip…

A 28-year-old man who is receiving lithium treatment for bipolar disorder becomes polyuric. His urine osmolarity is 90 mOsm/L; it remain at same level after he is given a nasal spray of ADH (dDAVP). What is the diagnosis?