A diploid organism (2n=8) undergoes meiosis. During meiosis…

A diploid organism (2n=8) undergoes meiosis. During meiosis I, nondisjunction occurs for one pair of homologous chromosomes, but meiosis II proceeds normally for all chromosomes. If one of the resulting gametes with an extra chromosome fertilizes a normal gamete, what would be the chromosome number in the zygote, and what genetic consequences might occur?

During DNA replication, the leading strand is synthesized co…

During DNA replication, the leading strand is synthesized continuously while the lagging strand is synthesized in Okazaki fragments. A mutation occurs in the gene encoding DNA ligase, reducing its activity by 90%. Additionally, primase function is slowed due to a chemical inhibitor. Which of the following best describes the expected consequences for DNA replication?