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Primary prevention programs are aimed at  

This assessment is a Paper 1 Style Assessment so you are NOT allowed to use a calculator. TOTAL AMOUNT OF TIME: 55 minutes Duration of assessment: 50 minutes Time allowed for scanning and uploading: 5 minutes

You are sequencing the genome of a novel Ebola virus variant.  You sequence 25,000 100bp reads using Illumina technology.  After aligning these sequences to the genome you find that you have an average coverage depth of 132.29 reads over each base pair.  What is the size of the Ebola genome?

You have been studying a section of a gene that has the following sequence in the template strand of DNA 3’-TAC GCT AGG CTT GTA CCC ACT – 5’ Which of the sequences below are the expected sequence of the mRNA?

Based on the codon table provided below what is the minimum number of single nucleotide substitutions that would be required to convert a Tyr to a Gly?

Fill in the blank with the most appropriate term that is described by the following statement: Can synthesize DNA from an RNA template  ______

Which of the drawings below is the most accurate depiction of transcription if the bottom strand is the template strand?

Which of the following statements is true about cancer genetics (one and only one is correct)?:  

A culture of bacteria is grown for many generations in a medium in which the only available nitrogen is the light isotope (14N).  The bacteria are then washed and transferred to a medium containing only 15N (the heavy isotope of nitrogen).  After two generations of growth in the 15N-containing medium, the cells are transferred back to 14N-containing medium for one final generation of growth.  After this final generation of growth in medium containing 14N, the cells are lysed, and their DNA is extracted and analyzed by equilibrium CsCl density gradient centrifugation.  What proportion of the DNA would be expected to “band” at each of the following densities in the gradient?    

The operon model for the regulation of enzyme synthesis concerned in lactose utilization  by Escherichia coli includes a regulator gene (I ),  a promoter (P ),  an operator region (O ), a structural gene (Z ) for the enzyme beta-galactosidase, and another structural gene (Y ) for b-galactoside permease.  Mutations in the lac operon have the following effects: Z  – and Y – mutant strains are unable to make functional beta-galactosidase and beta-galactoside permease, respectively, whereas I  – and O C mutant strains synthesize the lac operon gene-products constitutively.  For the following genotypes please indicate whether a functional beta-galactosidase gene will be expressed or not when the cells are grown with or without lactose present.  I + P  + O C Z -Y +