A client with severe rheumatoid arthritis has been receiving…

A client with severe rheumatoid arthritis has been receiving anakinra therapy for several months. During a follow-up visit, the nurse reviews the client’s clinical findings and laboratory data to monitor for immunosuppressive and inflammatory complications associated with this biologic agent. Which findings should the nurse recognize as potential adverse effects related to anakinra therapy? (Select all that apply.)

34-year-old woman, presents with persistent sadness, fatigue…

34-year-old woman, presents with persistent sadness, fatigue, and loss of interest in her usual activities for the past month. She reports difficulty sleeping, feelings of worthlessness, and occasional thoughts of self-harm. She denies any recent stressors or medical illnesses. Answer the following questions below.​ Questions:​ What additional assessment questions would you ask to evaluate her depressive symptoms?​ What physical and mental health conditions should be considered as differential diagnoses?​ Which screening tools could assist in evaluating her severity of depression?​ What laboratory tests might be ordered to rule out other contributing conditions?​ Based on her presentation, what pharmacologic and non-pharmacologic treatments would you consider?​ How would you monitor her response to treatment and address potential side effects?​ What patient education points should be emphasized regarding her condition and treatment plan?​ How would you approach safety assessment given her report of suicidal thoughts?