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A 22-year-old male patient weighing 72kg is receiving treatment in hospital for a severe exacerbation of asthma. Aminophylline has been prescribed and the respiratory registrar would now like to begin twice daily theophylline, aiming for a steady state plasma concentration of 10mg/L. The patient has an estimated theophylline clearance of 4L/h.   You calculate theophylline steady state plasma concentration using the following formula: Css = (S x F x D) / (Cl x T) Css = steady statement concentration (mg/L) S = salt factor = 1 F = bioavailability = 1 D = dose (mg) Cl = clearance (L/hour) T = dosing interval (hours)   The hospital dispensary has Uniphyllin (theophylline) available in 200mg, 300mg and 400mg strengths.   How many milligrams of theophylline should be prescribed to this patient every 12 hours?

A phase 3 clinical trial compares enlicitide to atorvastatin for the management of increased LDL cholesterol. In the atorvastatin group, the rate of patients who achieved a 50% reduction in cholesterol was 0.04. This increased to 0.2 in the group receiving the enlicitide.   Absolute risk reduction = treatment event rate – control event rate NNT (number needed to treat) = 1 / ARR   How many patients would need to be prescribed enlicitide for one patient to achieve a 50% reduction in LDL cholesterol?  

Which conditions are considered secondary causes of dyslipidemia?

A patient with breast cancer is prescribed docetaxel and capecitabine as described in the protocol below. The patient weighs 54kg and is 1.62m tall. The equation for calculating body surface area is available below: Extract from chemotherapy protocol Drug Dose Route Frequency Duration Docetaxel 75mg/m2 IV Day 1 only of a 21 day cycle 6 to 8 cycles of combination Capecitabine 1000mg/m2 twice daily Oral For 14 days from day 1 of cycle 6 to 8 cycles of combination   How many capecitabine 500mg tablets should the patient be prescribed for each 21-day cycle?

Medication review is an important part of evaluating fatigue because many commonly prescribed medications can contribute to symptoms.

Which of the following abbreviations is NOT a type of leukocyte?

An embolus is dangerous because it can ___

Which term means “condition of being without blood”?

Which of the following abbreviations is a type of cancer?

Which of the following abbreviations is a test that determines the number of antibodies against cell nuclei present in the bloodstream?