In this paper (Wilinski 2019), the researchers were studying…

In this paper (Wilinski 2019), the researchers were studying the difference in metabolic changes when transitioning from hunger to satiety state. In particular, they were interested in how the changes differed between CNS (fly heads) and systemic (fly bodies). In the following experiment, the researchers used two groups of flies: fasted and fed (refed). They separated the fly heads from the bodies and analyzed metabolites in each. The data is represented as heatmaps and using a color range: strong reductions in abundance are represented by deep blue, lesser reductions in light blue, whereas moderate increases are in pink, increasing to dark red which represents strong increases. Which of the following statements regarding these changes in metabolites is most accurate?

The following figure is taken from Cai 2025. In this experim…

The following figure is taken from Cai 2025. In this experiment, human patients were asked to ingest 3 types of chickpea: 1) Intact-C (chickpea meal in cell clusters), 2) Intact-S (chickpea meal processed so all cells are separated) and 3) Broken (chickpea cells are broken open). The researchers sampled GLP-1 and GIP for 180 minutes after the meal and also asked participants to report on their feelings of fullness. Error bars in the figure correspond roughly to significance (overlapping bars = no significant differences). Based on the figure, what clinical recommendations might you recommend to a patient asking about ways to lose weight?