A nurse practitioner orders an intravenous medication that i…

A nurse practitioner orders an intravenous medication that is highly bound to plasma proteins. Which statement best describes how high plasma protein binding affects the drug’s distribution?   Protein binding accelerates the rate at which the drug reaches target tissues.   Protein binding increases the drug’s ability to cross capillary membranes.   Protein binding limits the amount of free drug available to leave the plasma.   Protein binding enhances penetration of the drug across the blood-brain barrier. 

The nurse practitioner adds Ezetimibe (Zetia) to the patient…

The nurse practitioner adds Ezetimibe (Zetia) to the patient’s drug regimen. Based on the mechanism of action for this medication, it may lead to:   increased risk of rhabdomyolysis.   interference with absorption of other oral drugs.   hepatic enzyme elevation.   increased HDL-C levels.