A 62-year-old female presents with jaundice and the followin…

A 62-year-old female presents with jaundice and the following laboratory data:  Peripheral blood smear: macrocytosis, target cells  Platelet count: 355 x 10^9/L  PT: 25 sec (reference range = 10-14) PTT: 65 sec (reference range = 28-36) AST, ALT, total and direct bilirubin elevated  These clinical presentations and laboratory results are consistent with