A genetic counselor is meeting with two families, each with…

A genetic counselor is meeting with two families, each with a child diagnosed with hereditary deafness. Testing reveals that Family A’s child has a mutation in the GJB2 gene (connexin 26), while Family B’s child has a mutation in the MYO7A gene. Both children have similar severity of hearing loss. If the parents in Family A and Family B were to have children together, what would be the expected outcome for their offspring?

A patient with Lynch syndrome (hereditary non-polyposis colo…

A patient with Lynch syndrome (hereditary non-polyposis colorectal cancer) has a germline mutation in the MLH1 gene, which encodes a protein that is involved in the mismatch repair process. Which type of mutations would accumulate most rapidly in this patient’s cells?