An ARDS patient is being managed with a lung-protective vent…

An ARDS patient is being managed with a lung-protective ventilation strategy. Which interventions may help reduce ventilator-induced lung injury?   I. Accepting permissive hypercapnia when necessaryII. Using appropriately selected PEEP to maintain alveolar recruitmentIII. Using smaller tidal volumes based on predicted body weightIV. Using pressure-controlled ventilation when clinically appropriate to limit airway pressure