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Answer all the questions in the attached quiz file

Which lipid-lowering medication works by inhibiting intestinal cholesterol absorption? 

Which direct oral anticoagulant is most dependent on renal clearance and should be avoided in patients with severe renal impairment? 

A 72-year-old patient with mild prostate enlargement and significant urinary hesitancy seeks treatment. Which medication class is most appropriate for initial symptom relief?

Which medication should be avoided in a patient with HFrEF due to worsening cardiac function?

A 58-year-old patient with newly diagnosed uncomplicated hypertension has no significant past medical history. Which medication class is considered a first-line option for initial therapy?

A 68-year-old patient with acute decompensated heart failure presents with dyspnea, bilateral lower extremity edema, and jugular venous distension. The patient has been taking oral furosemide 40 mg twice daily at home. Intravenous furosemide is initiated. Which mechanism best explains why loop diuretics produce greater natriuresis than thiazide diuretics in this clinical setting?

A 52-year-old patient with moderate vasomotor symptoms is considering hormone therapy. She has an intact uterus and no significant cardiovascular or thromboembolic risk. Which regimen is most appropriate?

A 70-year-old patient with newly diagnosed nonvalvular atrial fibrillation is started on apixaban for stroke prevention. Which of the following best describes the mechanism of action of this medication?

A 66-year-old patient with chronic stable angina continues to have exertional chest pain despite maximally tolerated doses of a beta-blocker and long-acting nitrate therapy. The patient’s blood pressure is 98/60 mmHg and heart rate is 58 bpm. Which of the following is the most appropriate next medication to improve anginal symptoms without further lowering heart rate or blood pressure?