True or False? Since we know hormones which are lipophilic,…

True or False? Since we know hormones which are lipophilic, like the steroid hormones, are transported in the blood via carrier proteins, this means they must have much shorter half-lives than ones which dissolve in plasma, like the peptide hormones. Hint: think of an example of a steroid hormone and a peptide hormone and ask yourself which one remains in circulation longer before being broken down, recycled and/or excreted.

The following class of drugs (brand name of the most common…

The following class of drugs (brand name of the most common is Viagra) were initially used to treat cardiovascular complications through vasodilation but a side effect led to their employment in erectile dysfunction, however, some patients, including females, may also be taking this medication, for example, to treat pulmonary hypertension, and thus need to be considered when administering nitroglycerin for angina pectoris during a suspected acute MI, given this medication can lead to excessive vasodilation.

Per your clinical case question in the digestive lab, the ut…

Per your clinical case question in the digestive lab, the utility of bile acid sequestrant drugs goes beyond treating bile acid diarrhea, and in fact preventing enterohepatic recirculation of bile acids with these drugs is also beneficial in treating high levels of blood cholesterol (hypercholesterolemia). Why?