A physiological undergraduate working in a neuroscience labo…

A physiological undergraduate working in a neuroscience laboratory is asked to pick up a model of the human brain and point to the general area dedicated to processing sensory and motor information. Knowing how the brain is organized, how may the student respond?

While traditional antipsychotics primarily modulate dopamine…

While traditional antipsychotics primarily modulate dopaminergic and serotonergic signaling, the cholinergic hypothesis of schizophrenia posits that muscarinic receptor dysfunction contributes to psychosis and cognitive impairment. The recently FDA-approved combination xanomeline-trospium represents the first mechanistically novel antipsychotic approach outside of dopamine blockade. What is the therapeutic mechanism of action for this agent?

Combined increases in behavioral activation and mesolimbic d…

Combined increases in behavioral activation and mesolimbic dopamine release is observed following cocaine administration.  Although an increase in behavioral activation continues to present following chronic cocaine administration, a reduction in dopamine is observed. Which of the following is accurate regarding the above statements?