Author: Anonymous

A 71-year-old female with severe COPD (FEV₁ 38% predicted) presents for follow-up. She has chronic bronchitis symptoms and reports two hospitalizations for COPD exacerbations in the past year despite adherence to triple inhaler therapy (fluticasone/umeclidinium/vilanterol). She quit smoking 3 years ago. FEV 1= 42%. Blood eosinophil count is 90 cells/µL. She denies asthma history. Oxygen saturation is 93% on room air. BMI is 21 kg/m². Which of the following is the most appropriate next step in pharmacologic management?  

A 65-year-old patient with isolated systolic hypertension is prescribed amlodipine. Which of the following adverse effects is most commonly associated with this medication?  

A 29-year-old female at 9 weeks gestational pregnancy presents with palpitations, weight loss, tremor, and heat intolerance. Laboratory evaluation reveals suppressed TSH and elevated free T4. Thyroid-stimulating immunoglobulins are positive. She is diagnosed with Graves disease. Which of the following is the most appropriate initial pharmacologic management?  

Drug therapies for the treatment of asthma are directed at the three major pathophysiologic abnormalities that include (Select all that apply): 

Which of the following agents should not be used as rescue therapy in exercised-induced asthma(EIA)? 

JT is a 48 yo with a history of gastrointestinal bleed, hypertension, hyperlipidemia, type II diabetes mellitus, and obesity. He presents to the clinic for pain management for his hip osteoarthritis.  He has tried acetaminophen and topical Voltaren (diclofenac) for the past six months and he is receiving no relief. It was determined that his cardiovascular risk profile is too high to consider a Cox-2 inhibitor. Which of the following NSAIDS would present the lowest risk of gastrointestinal adverse events for JT?   

Which medication provides a protective barrier over ulcers, promoting healing without directly affecting acid production? 

In the treatment of Helicobacter pylori-associated peptic ulcer disease, which combination of therapies is commonly recommended as first line treatment? 

BN is a 66 yo female with diagnosed COPD. She remains stable without exacerbations on Trelegy inhaler (fluticasone, umeclidinium, and vilanterol) one inhalation once daily. If this patient was diagnosed and treated by the current GINA guidelines, we can assume that she: 

Tramadol, a commonly used drug in osteoarthritis, is a synthetic opioid.  Which of the following is not an adverse effect of Tramadol?