Author: Anonymous

You have discovered what you think is a new herpesvirus. You have a tube of serum containing the potential virus. When you have looked at it using electron microscopy, you see what you think are herpesvirus particles, at a concentration of about 2.4 x 109 particles/ml. But this does not always equate with titer. What assay would you typically use to figure out the titer of your virus in your serum sample?

What is the primer for picornavirus RNA replication? 

Which of the following features is true of all picornavirus virions ?

Which of the following does not represent a barrier to infection of the lung?

Palbociclib is a pharmaceutical drug used to treat certain types of breast cancer. Consider the structure of palbociclib (shown below) and answer the questions that follow. What is the hybridization of the nitrogen atom labeled A? [hybridA]  What is the hybridization of the nitrogen atom labeled B? [hybridB]  What is the hybridization of the nitrogen atom labeled C? [hybridC]  There are eleven (11) lone pairs of electrons in palbociclib. How many of these lone pairs are delocalized in resonance? [LPdelocalized]  How many of these lone pairs reside in hybrid orbitals? [LPhybrid]  Which of the nitrogen atoms, A, B, or C, would be the most basic? [BasicN] 

The neurotransmitter epinephrine, also known as adrenaline, is involved in regulating visceral functions (e.g., respiration) and plays an important role in the fight-or-flight response in many animals. Consider the structure of N-protonated epinephrine (shown below) and answer the following questions. The lowest-energy conformation of N-protonated epinephrine is stabilized by hydrogen bonding between the hydroxyl and the ammonium group. Which of the following Newman projections (A-F) represents this conformation viewed through the C1-C2 bond? [conformation]  Recall that dihedral angles are measured clockwise when answering the next two questions. Consider the conformation of N-protonated epinephrine in which the aryl (Ar) substituent and the ammonium group are eclipsed. What is the dihedral angle between hydroxyl group and ammonium group in this conformation? [dihedral1] What is the dihedral angle between the aryl (Ar) substituent and the ammonium group in Newman structure B? [dihedral2] Do Newman structures A and C represent conformational isomers? [isomers]

Classify each of the following as either a Brønsted-Lowry acid, Lewis acid, or neither. A: [molA] B: [molB] C: [molC] D: [molD]

Which of the following is the correct formula you should type in Excel to calculate the forecast for 2021 using a simple moving average forecast method with five periods (the formula needs to be entered in a way that allows to calculate the forecasts for the other years as well). All references refer to the cells in the file you downloaded for this exhibit.

Please forecast the demand for 2021 using a weighted moving average forecast method. The most recent period has a weight of 0.6, and the other periods included in the forecast have a weight of 0.1. Round your answer to the closest whole number.

ACADEMIC INTEGRITY By taking this exam, you understand that you are not allowed to access any resources other than the Midterm Exam on Canvas, the formula sheet provided with the exam, and the Excel files provided within the exam. You understand that your actions on this computer are being recorded during the whole exam, and accessing any unauthorized resource (online, offline or outside of your computer) during the exam will lead to an unforgivable F for this course. Please note that Honorlock will shortly pause the exam when you start downloading the Excel files, and this is a normal behavior of Honorlock, so do not worry if this happens. Shortly after the download started, Honorlock will prompt you to relaunch the exam. You will not need to perform any ID verification step, so this a quick process. Before continuing with the exam, please close all other applications and files on your computer. Good luck!