Author: Anonymous

In which of the following stages are the Ig genes for the light chain still in their germline configuration?

You would expect to see Igα and Igβ genes turned on (expressed) during the large pre-B cell stage.

Which gene segment is located within the α-chain locus and is consequently deleted and inactivated once the α gene rearranges it’s gene segments?

Once expression of RAG-1 and RAG-2 genes are turned on, expression is never turned off.

Imagine you’re a doctor and you discover your infant, recently born patient has thrush. You order genetic sequencing and find that the RAG-1 gene doesn’t produce a functional enzyme.  From what you have learned in this class and with this information at hand, you can conclude that:

Once expression of RAG-1 and RAG-2 genes are turned on, expression is never turned off.

Imagine you’re a doctor and you discover your infant, recently born patient has thrush. You order genetic sequencing and find that the RAG-1 gene doesn’t produce a functional enzyme.  From what you have learned in this class and with this information at hand, you can conclude that:

MHC I binding site is formed from the (α) alpha 1 and (β) beta 1 subunits.

Which of the following subsets of B-cells is the most abundant?

Which of the following is false about the light chain gene rearrangement?