Author: Anonymous

The structure below is D-ala-D-ala dipeptide. What is its function?

What is the MOA of cycloserine? Check all that apply

Polyenes (amphotericin & nystatin) bind to membrane sterols and form pores that kill fungal cells. Which class of antibiotics has a similar mechanism of action? 

Sulfadoxine-pyrimethamine drugs are always given in combination. These drugs directly target [pathway]. Sulfadoxine targets [target1] while pyrimethamine targets [target2].

The structure below is D-ala-D-ala dipeptide. What is its function?

Nonnucleoside reverse transcriptase inhibitors bind to the reverse transcriptase catalytic site.

What is the function of CLSI? (check all that apply)

Polyenes (amphotericin & nystatin) bind to membrane sterols and form pores that kill fungal cells. Which class of antibiotics has a similar mechanism of action? 

Atovaquone acts on the cytochrome bc1 complex and inhibits the electron transport chain. 

Cancer cells treated with a newly developed drug (Gr8) began to show resistance. After running a couple of PCR reactions you’ve noticed that one of the cytochrome P450 genes (CYP-g8or) is highly upregulated in resistant cells only. You decided to knock down the gene with siRNA. What is most likely the effect that this downregulation will have?