An adult female patient with a history of recurrent UTIs was…

An adult female patient with a history of recurrent UTIs was diagnosed with a UTI 3 days ago and began a 5 day course of empiric trimethoprim-sulfamethoxazole (TMP-SMX). The urine was sent for culture and results are now available:  Culture results: E. Coli >100,000 CFU/mL Sensitivity Report:  Antibiotic  Sensitivity  Ampicillin R Cefuroxime S Nitrofurantoin S TMP-SMX R Ciprofloxacin S Based on the sensitivity report, what is your next step?