A 58-year-old male presents with progressive headaches, seiz…

A 58-year-old male presents with progressive headaches, seizures, and focal neurological deficits. Imaging reveals a mass in the frontal lobe that crosses the corpus callosum. The biopsy confirms a diagnosis of glioblastoma multiforme. Which of the following best describes this type of tumor?

A 27-year-old marathon runner collapses near the finish line…

A 27-year-old marathon runner collapses near the finish line on a hot day. On arrival to the emergency department, his core temperature is 41.2°C (106°F). He is confused, tachycardic, and not sweating. Which of the following best explains the pathophysiology of his condition?