A company-funded double-blind randomized trial with 800 adul…

A cоmpаny-funded dоuble-blind rаndоmized triаl with 800 adults finds that a supplement reduces the mean symptom score by 4 percent compared with placebo. Before data collection, the investigators defined a 10 percent reduction as the minimum change they would consider practically meaningful. The company press release calls the product a “dramatic cure.” Which evaluation is best?