A 35-year-old patient is undergoing a routine complete blood…
Questions
A 35-yeаr-оld pаtient is undergоing а rоutine complete blood count (CBC) as part of a follow-up for a known metabolic disorder. The patient reports no current symptoms such as fever or infection. Physical examination is unremarkable.Laboratory Findings:WBC count: 8.5 × 10³/µL (Reference: 4.5–11.0 × 10³/µL)Differential: Normal distribution of neutrophils, lymphocytes, and monocytesPeripheral smear: Large, dark-staining granules present in neutrophils, lymphocytes, and monocytes; granules resemble toxic granulation but are coarse and uniformly distributedPlatelet count: NormalRBC morphology: NormalClinical history: Patient has Hurler syndrome (a mucopolysaccharidosis)Which condition best explains these findings?