A 24-year-old woman with bipolar I disorder has been stable…
Questions
A 24-yeаr-оld wоmаn with bipоlаr I disorder has been stable on valproate 1000 mg daily for the past year. She presents today and reports she is planning to become pregnant within the next 6 months. She asks about the safety of continuing her current medication. Which of the following is the most important concern regarding valproate use during pregnancy?