Module 5 A postsynaptic neuron normally receives both excita…

Mоdule 5 A pоstsynаptic neurоn normаlly receives both excitаtory input and inhibitory input mediated by GABA. A mutation prevents the GABA receptors from opening their Cl⁻ channels, but excitatory synapses continue to function normally. Using this scenario, analyze how loss of inhibitory signaling affects neural communication. In your response: Predict how the mutation will affect the postsynaptic membrane potential. Explain how the loss of inhibitory input changes the summation of graded potentials. Predict how the mutation will affect the likelihood that the neuron reaches threshold and generates action potentials. Explain why this type of disruption could produce excessive neural activity.