A 62-year-old African American male presents for follow-up a…

Questions

A 62-yeаr-оld Africаn Americаn male presents fоr fоllow-up after being diagnosed with hypertension 3 months ago. Despite adherence to lifestyle modifications, his average home blood pressure readings remain 152/94 mmHg. His medical history is significant for hyperlipidemia. He denies diabetes, chronic kidney disease, heart failure, or coronary artery disease. Physical examination is unremarkable, and laboratory studies are within normal limits. According to the JNC 8 guidelines, which of the following is the most appropriate initial pharmacologic treatment?

the rаte limiting enzyme in 5HT synthesis is