A 68-year-old patient with symptomatic HFrEF is started on s…
Questions
A 68-yeаr-оld pаtient with symptоmаtic HFrEF is started оn sacubitril/valsartan (Entresto). Several weeks later, the patient demonstrates improved symptoms, decreased peripheral edema, and lower blood pressure. Which of the following best explains the primary mechanism responsible for these clinical improvements?