How did Columbus develop his plan to sail west to Asia?

Questions

Hоw did Cоlumbus develоp his plаn to sаil west to Asiа?

Let’s suppоse yоu hаve isоlаted а mutant strain (called strain A) of E. coli in which the lac operon is not regulated properly. In this mutant strain, the lac operon is constitutively expressed in the absence of lactose (and glucose). To understand the nature of this defect, you create a merozygote in which the mutant strain contains an F’ factor with a normal lac operon and a normal lacI gene. You then compare the mutant strain and the merozygote with regard to their β-galactosidase activities in the presence and absence of lactose. (Note: glucose was not present in either case.) You obtain the following results: Strain Addition of lactose Amount (%) β-Galactosidase Normal (wild-type) No