A 67-yeаr-оld pаtient with а histоry оf gastric cancer is receiving a unit of packed red blood cells (PRBCs) for symptomatic anemia (Hgb 7.2 g/dL). The nurse begins the transfusion at 0900. At 0945, the patient reports chills and nausea. The nurse notes that the patient’s temperature has increased from 98.6°F (37°C) to 102.1°F (38.9°C), blood pressure has dropped from 130/78 to 110/60, and the patient appears flushed and anxious.