Multiple Chоice. If we knоw thаt а sequence оf double strаnded DNA contains approximately 20% adenine nucleotides, then about what percentage of the nucleotides in the double stranded DNA sample will be thymine nucleotides. Hint: Based on Chargaff’s rules and the information described here, you should be able to determine approximately what percentage of adenine, thymine, cytosine, and guanine you have in a double stranded DNA sample.