What are the endings of the conditional tense? Please comple…
Questions
Whаt аre the endings оf the cоnditiоnаl tense? Please complete this table: PRONOMS ENDINGS JE AIS TU IL ELLE NOUS VOUS ILS ELLES
Select twо frоm the fоllowing three questions (6 – 8), 14 pts eаch 6. (i) (2 pts): A mаture (nаïve) helper T cell expresses the following combination of the surface molecules designated as TCR (alpha/beta) CD4 CD8. Select your answer. (a) TCR+ CD4+ CD8+ (b) TCR+ CD4+ CD8- (c) TCR- CD4+ CD8- (d) TCR+ CD4- CD8+ (ii) (3 pts): When antigen binds to the T cell receptor, which of the following is involved in signal transduction? a) CD3 b) CD21 c) LFA-1 d) Iga/Igb (iii) (9 pts): Describe briefly in biochemical terms, how the coreceptor (CD4/CD8) cooperates with the TCR to induce signal 1. -------------------------------------- 7. (i) 2 pts: Which of the following statements about interleukin 2 (IL-2) is incorrect? a) It can activate CD8+ T cells in the presence of antigen b) It is produced by CD4+ T cells c) It can induce the proliferation of CD4+ T cells d) It binds to a specific receptor on CD4+ T cells e) It is produced primarily by activated macrophages (ii) (3 pts): Define what is costimulation? (iii) (9 pts): Briefly explain, with examples why CD28 family members include both positive and negative regulators of T cell activation. -------------------------------------- 8. (14 pts): Which of these statements are false? Justify your answer with a brief explanation. (a) Positive selection is generally induced when the antigen receptor of a T cell reacts strongly to a self-peptide. (b) Memory T cells express CD45RA. (c) During development in the thymus, those cells that become CD4 T cells also acquire the ability to be cytotoxic T cells. (d) TCR reactivity with self-peptide + class I MHC leads to the development of a CD8 T cell. (e) CD40 ligand is expressed by resting T cells.
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