Cаse Study 5: Trаumаtic Amputatiоn with Abоve-Knee Prоsthetic (D.H.) Scenario: D.H., a 28-year-old motorcyclist, sustained a traumatic above-knee amputation of his right leg following a high-speed accident. He is fitted with an above-knee prosthetic with a knee joint and pylon to restore walking ability. The prosthetic compensates for the lost limb, providing stability and controlled knee flexion for a natural gait. 5.5 Which glial cells in the central nervous system are responsible for producing myelin? Understanding how myelin affects nerve signal transmission is important when considering phantom limb sensations, nerve pain, and overall neuromuscular function in rehabilitation.
Cаse Study 2: Amputаtiоn with Belоw-Knee Prоsthetic (M.L.) Scenаrio: M.L., a 45-year-old diabetic patient, underwent a below-knee amputation due to severe peripheral vascular disease complications. She uses a below-knee prosthetic to restore mobility and independence, relying on a custom socket and pylon system for weight-bearing and ambulation. Recently, her endocrinologist suspects a pituitary tumor due to hormonal imbalances from poorly controlled diabetes, which could impact her prosthetic rehabilitation by affecting her vision. 2.8 Which neurotransmitter is typically excitatory at the neuromuscular junction? If M.L has neuropathy (from diabetes) or muscle weakness (due to metabolic dysfunction from the pituitary tumor), this neurotransmitter signaling may be impaired. This could cause reduced muscle activation in the residual limb, leading to instability, poor prosthetic control, and compensatory gait patterns.