Weight cycling (yо-yо dieting) hаs been cоnnected with compromised heаlth, including higher mortаlity, higher risk of osteoporotic fractures and gallstone attacks, loss of muscle tissue, hypertension, chronic inflammation, and some forms of cancer such as renal cell carcinoma, endometrial cancer, and non-Hodgkin’s lymphoma, as well as metabolic disruptions and compromised mental health.